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Collaborators of The Myelin Group

International  National (Finland)    Local (Oulu)

*** IMPORTANT ***
On this page, we include and acknowledge the other research groups that have contributed, or are currently contributing, to the research activity of The Myelin Group. In some cases, these collaborations have already given rise to publications (links provided), while others are still in the active, pre-publication, research phase (only information of a general nature is given, along with links to the groups' web sites, if available).

Groups with which we have only submitted applications for Project Funding (and are awaiting decisions) are NOT included here.

In order to preserve confidentiality, we do not include unpublished details of the collaborations in which The Myelin Group is contributing, or has contributed, to the research  projects of other groups.

Since the policy of many Journals tends to exclude the inclusion of scientists in the list of authors who have "only" contributed certain materials (e.g. antibodies, plasmids, ... ) to the published work, we take the opportunity of publicly acknowledging these scientists on this page. Indeed, their contributions are, or have been, very important to the acquisition of meaningful data, without which the work would not be publishable.

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International Collaborators
Claude Cassagne (France)
Bertrand Garbay (France)
Morimitsu Nishikimi (Japan)
Eduardo Nobile-Orazio (Italy)
Klaus Petry (France)
Richard Quarles (U.S.A.)
Barbara Ranscht (U.S.A.)
Françoise Sargueil (France)
Jan Sedzik (Sweden)
Nicole Schaeren-Wiemers (Switerland)
Jean-Michel Vallat (France)
 

Claude CASSAGNE, Bertrand GARBAY and Françoise SARGUEIL (University of Bordeaux 2, France)

My postgraduate training and early post-doctoral career was spent in the laboratory of Membrane Biogenesis under the guidance of Professor Claude Cassagne. Since leaving France in 1995, I have maintained regular contact with the great team he created and we have collaborated in several instances. Notably, Bertrand Garbay (now a professor) provided the Myelin Group with the sciatic nerve cDNA from which we have developed our MAG cytoplasmic domain fusion protein constructs, and also collaborated in the independent analysis of the S-MAG cytoplasmic domain dimorphism in mice, which was included in the first publication of the Myelin Group in 1998. Françoise Sargueil has done some lipid analyses for us in our attempt to characterize our native MAG preparations. We have also written a couple of review articles (Review 1, Review 2) together.

Morimitsu NISHIKIMI (Wakayama Medical College, Japan)

Provided us with the GST-S100b plasmid construct employed in our publication reporting the direct interaction between the L-MAG cytoplasmic domain and S100b.

Eduardo NOBILE-ORAZIO (University of Milan, Italy)

Trained Satu Päiväläinen (a Myelin Group member) for two months (2001) in the establishment and maintenance of myelinating DRG/Schwann cell cocultures in his lab. This powerful model is currently being exploited in the Myelin Group for the analysis of molecular and cellular processes implicated in PNS myelinogenesis.

Klaus PETRY (University of Bordeaux 2, France)

Provided a sciatic nerve cDNA expression library which we employed in our earlier attempts to identify MAG ligands. The lack of success we had with this approach does not reflect the quality of the expression library!

Richard QUARLES (BNP, DIR, NINDS, NIH, Bethesda, USA)
The discoverer of MAG in the early 1970s, provided us with the S16 and S16Y Schwann cell lines with which we did our first immunocytochemistry analyses of MAG, included in our publication demonstrating the interaction between the S-MAG cytoplasmic domain and tubulin. He has also provided us with very useful comments concerning our data and manuscripts. Web page & Another.

Barbara RANSCHT (University of California, San Diego, USA)

Has provided us with her famous anti-galactosyl cerebroside antibody, which works extremely well in our myelinating cultures. Results obtained using this antibody have already been presented in poster form at the 2003 IBRO meeting in Prague, and will also figure in a manuscript that we will be submitting for publication shortly.

Jan SEDZIK (University of Uppsala, Sweden)

Is collaborating with us on the structural analysis of MAG.

Nicole Schaeren-Wiemers (University Hospital of Basel, Switzerland)

Has provided us with the GFP/MAG constructs which we will be employing in our research. Web page & Another.

Jean-Michel VALLAT (University of Limoges, France)

Performed immuno-electron microscopy analyses for us when we were evaluating the performance of our anti-MAG cytoplasmic domain-specific polyclonal antibodies. They work! We have also collaborated in a study published by his group on the expression of MAG in CNS myelinating cocultures. Web page.
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National Collaborators (Finland)
Sirku PELTONEN (University of Turku)  collaborated in the setting up of the MMDC.

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Local Collaborators (Oulu)
Kalervo HILTUNEN (Dept. of Biochemistry, University of Oulu) helped with the CD spectroscopy employed in the publication dealing with the S-MAG interaction with tubulin. Web page.
Juha PELTONEN (Dept. of Anatomy, University of Oulu) collaborated in the setting up of the MMDC.    Web page.
Peter NEUBAUER (Bioprocess Engineering Laboratory, University of Oulu) is participating in the Schwann cell production for the MMDC. Web page
The PATHOLOGISTS (Dept. of Pathology, University Hospital of Oulu), who provide us with much needed material.


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