3D medical imaging
The project focuses of statistical analyses of craniofacial structures from 3D images of human heads. The first problem considered was to study the feasibility of automatic recognition from the 3D models of faces if a pair of twins is monozygotic or dizygotic. The next study involved development of methods to measure infant head shape deformities where the goal was to use new 3D digital surface imaging innovatively in early asymmetry diagnostics. We have also developed a new scale space method, SphereSiZer, for spherical data.
(A) Female twin pair regarded as DZ by DNA, but MZ by 3D analysis. (B) Female twin pair regarded as MZ by DNA, but DZ by 3D analysis. (C) Male twin pair regarded as MZ by DNA and 3D analysis. (D) Male twin pair regarded as DZ by DNA and 3D analysis.
Selected papers:
- V. Vuollo, M. Sidlauskas, A. Sidlauskas, V. Harila, L. Salomskiene, A. Zhurov, L. Holmström, P. Pirttiniemi, and T. Heikkinen. Comparing Facial 3D Analysis to DNA Testing in Recognition of Twin Zygosity. Twin Research and Human Genetics, 18:306-313, 6 2015. Available on-line at http://dx.doi.org/10.1017/thg.2015.16.
- V. Vuollo, L. Holmström, H. Aarnivala, V. Harila, T. Heikkinen, P. Pirttiniemi, and A. M. Valkama. Applying kernel density estimation on a sphere to analyze asymmetry and flatness in head shape. Statistics in Medicine, 35(26):4891-4904, 2016. Available on-line at http://dx.doi.org/10.1002/sim.7032.
- H. Aarnivala, V. Vuollo, V. Harila, T. Heikkinen, P. Pirttiniemi, L. Holmström, and A. M. Valkama. The course of positional cranial deformation from 3 to 12months of age and associated risk factors: a follow-up with 3D imaging. European Journal of Pediatrics, 175(12):1893 - 1903, 2016. Available on-line at http://dx.doi.org/10.1007/s00431-016-2773-z.
- H. Aarnivala, V. Vuollo, T. Heikkinen, V. Harila, L. Holmström, P. Pirttiniemi, and A. M. Valkama. Accuracy of measurements used to quantify cranial asymmetry in deformational plagiocephaly. Journal of Cranial-Maxillo-Facial Surgery, 45(8):1349 - 1356, 2017. Available on-line at http://dx.doi.org/10.1016/j.jcms.2017.05.014.
- V. Vuollo and L. Holmström. A scale space approach for exploring structure in spherical data. Computational Statistics & Data Analysis, 125:57 - 69, 2018. Available on-line at https://doi.org/10.1016/j.csda.2018.03.014.